Clot Dissolution

Once coagulation has caused the formation of a clot the body will naturally commence a process called fibrinolysis, which causes the enzyme Plasmin to hydrolyse (break up) fibrin clots.

Basically, Plasmin is released from inactive Plasminogen (which circulates freely around the circulatory system in blood)

– Plasminogen causes the release of Plasmin

– Plasmin breaks down the fibrin molecule

-Fibrin – then becomes small enough that phagocytosis can start to remove the connective tissue through the blood stream.